BDBM50189741 5-[5-(2,5-dihydroxyphenyl)furan-2-ylmethylene]thiazolidine-2,4-dione::CHEMBL211819

SMILES Oc1ccc(O)c(c1)-c1ccc(\C=C2/SC(=O)NC2=O)o1

InChI Key InChIKey=VCBZVSWEFHPAJX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50189741   

LigandPNGBDBM50189741(5-[5-(2,5-dihydroxyphenyl)furan-2-ylmethylene]thia...)
Affinity DataIC50: 20nMAssay Description:Inhibition of PI3Kgamma (unknown origin) assessed as decrease in fluorescence intensity using phosphorylated substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50189741(5-[5-(2,5-dihydroxyphenyl)furan-2-ylmethylene]thia...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50189741(5-[5-(2,5-dihydroxyphenyl)furan-2-ylmethylene]thia...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human PI3KgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed