BDBM50189300 CHEMBL3826996

SMILES CCOC(=O)c1cc(C(=O)\C=C\c2ccc(cc2)-c2ccccc2)n2ccc(OC)cc12

InChI Key InChIKey=UZBXGBBGRVAPNZ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50189300   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Alexandru Ioan Cuza University

Curated by ChEMBL

LigandBDBM50189300(CHEMBL3826996)Copy SMILESCopy InChI

Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of human recombinant farnesyltransferase using farnesylpyrophosphate and dansyl-GCVLS as substrate measured for 15 mins by fluorescence as...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
10/11/2017
Entry Details Article
Copy Entry DOIPubMed
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TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Alexandru Ioan Cuza University

Curated by ChEMBL

LigandBDBM50189300(CHEMBL3826996)Copy SMILESCopy InChI

Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of FTase (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/20/2021
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL