BDBM50189296 CHEMBL3827509

SMILES COc1cc(\C=C\C(=O)c2cc(C(O)=O)c3c(C)cc(C)cn23)cc(OC)c1OC

InChI Key InChIKey=DLBJTGOEYREYFT-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50189296   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Alexandru Ioan Cuza University

Curated by ChEMBL

LigandBDBM50189296(CHEMBL3827509)Copy SMILESCopy InChI

Affinity DataIC50: 1.59E+4nMAssay Description:Inhibition of human recombinant farnesyltransferase using farnesylpyrophosphate and dansyl-GCVLS as substrate measured for 15 mins by fluorescence as...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
10/11/2017
Entry Details Article
Copy Entry DOIPubMed
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TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Alexandru Ioan Cuza University

Curated by ChEMBL

LigandBDBM50189296(CHEMBL3827509)Copy SMILESCopy InChI

Affinity DataIC50: 1.59E+4nMAssay Description:Inhibition of FTase (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/20/2021
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL