BDBM50188952 CHEMBL379830::N,N,N-trimethyl-2-(4-styrylphenoxy)ethanaminium

SMILES C[N+](C)(C)CCOc1ccc(\C=C\c2ccccc2)cc1

InChI Key InChIKey=LSHCDRJBFRVFPC-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50188952   

TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50188952(N,N,N-trimethyl-2-(4-styrylphenoxy)ethanaminium | ...)
Affinity DataIC50: 34nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50188952(N,N,N-trimethyl-2-(4-styrylphenoxy)ethanaminium | ...)
Affinity DataKi:  306nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human alpha7 nAChR expressed in SH-SY5Y cells membrane assessed as inhibition constant preincubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50188952(N,N,N-trimethyl-2-(4-styrylphenoxy)ethanaminium | ...)
Affinity DataKi:  1.53E+3nMAssay Description:Displacement of [3H]-epibatidine from human alpha3beta4 nAChR expressed in SH-EP1 cells membrane assessed as inhibition constant preincubated for 5 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50188952(N,N,N-trimethyl-2-(4-styrylphenoxy)ethanaminium | ...)
Affinity DataKi:  2.17E+3nMAssay Description:Displacement of [125I]iodo-MLA from alpha-7 nAChR in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed