BDBM50188879 CHEMBL214057::rac-8-[1-(4-fluoro-phenyl)-cyclohexyl]-4-propyl-2,8-diaza-spiro[4.5]decan-1-one

SMILES CCCC1CNC(=O)C11CCN(CC1)C1(CCCCC1)c1ccc(F)cc1

InChI Key InChIKey=YGXIRUYGAMKSJZ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50188879   

TargetSodium- and chloride-dependent glycine transporter 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188879(rac-8-[1-(4-fluoro-phenyl)-cyclohexyl]-4-propyl-2,...)
Affinity DataEC50:  93nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188879(rac-8-[1-(4-fluoro-phenyl)-cyclohexyl]-4-propyl-2,...)
Affinity DataIC50: 3.03E+3nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed