BDBM50188854 4-(4-fluoro-phenyl)-8-[1-(3-trifluoromethoxy-phenyl)-cyclohexyl]-2,8-diaza-spiro[4.5]decan-1-one::CHEMBL214083

SMILES Fc1ccc(cc1)C1CNC(=O)C11CCN(CC1)C1(CCCCC1)c1cccc(OC(F)(F)F)c1

InChI Key InChIKey=RQXAELXRNCKUCJ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50188854   

TargetSodium- and chloride-dependent glycine transporter 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188854(4-(4-fluoro-phenyl)-8-[1-(3-trifluoromethoxy-pheny...)
Affinity DataEC50:  1.67E+4nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188854(4-(4-fluoro-phenyl)-8-[1-(3-trifluoromethoxy-pheny...)
Affinity DataEC50:  1.67E+4nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed