BDBM50188850 CHEMBL426502::rac-8-bicyclohexyl-1-yl-4-phenyl-2,8-diaza-spiro[4.5]decan-1-one

SMILES O=C1NCC(c2ccccc2)C11CCN(CC1)C1(CCCCC1)C1CCCCC1

InChI Key InChIKey=WSUGJUNQSQGAGH-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50188850   

TargetSodium- and chloride-dependent glycine transporter 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188850(rac-8-bicyclohexyl-1-yl-4-phenyl-2,8-diaza-spiro[4...)
Affinity DataEC50:  1.52E+4nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed