BDBM50188843 8-(1-phenyl-cyclohexyl)-4-propyl-2,8-diaza-spiro[4.5]decan-1-one::CHEMBL213683::CHEMBL540110::rac-8-(1-phenyl-cyclohexyl)-4-propyl-2,8-diaza-spiro[4.5]decan-1-one

SMILES CCCC1CNC(=O)C11CCN(CC1)C1(CCCCC1)c1ccccc1

InChI Key InChIKey=XNZWDRHJBZFXLY-UHFFFAOYSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50188843   

TargetMu-type opioid receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188843(CHEMBL213683 | CHEMBL540110 | rac-8-(1-phenyl-cycl...)
Affinity DataIC50: 2.73E+3nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188843(CHEMBL213683 | CHEMBL540110 | rac-8-(1-phenyl-cycl...)
Affinity DataIC50: 2.76E+3nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188843(CHEMBL213683 | CHEMBL540110 | rac-8-(1-phenyl-cycl...)
Affinity DataEC50:  62nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188843(CHEMBL213683 | CHEMBL540110 | rac-8-(1-phenyl-cycl...)
Affinity DataEC50:  82nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188843(CHEMBL213683 | CHEMBL540110 | rac-8-(1-phenyl-cycl...)
Affinity DataIC50: 2.76E+3nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed