BDBM50188810 (R)-4-phenyl-8-((1S,2S)-2-phenyl-cyclohexyl)-2,8-diaza-spiro[4.5]decan-1-one::CHEMBL386658

SMILES O=C1NC[C@H](c2ccccc2)C11CCN(CC1)[C@H]1CCCC[C@H]1c1ccccc1

InChI Key InChIKey=MMAYPVADBNWURJ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50188810   

TargetSodium- and chloride-dependent glycine transporter 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188810((R)-4-phenyl-8-((1S,2S)-2-phenyl-cyclohexyl)-2,8-d...)
Affinity DataEC50:  61nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188810((R)-4-phenyl-8-((1S,2S)-2-phenyl-cyclohexyl)-2,8-d...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]NOP from human NOP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188810((R)-4-phenyl-8-((1S,2S)-2-phenyl-cyclohexyl)-2,8-d...)
Affinity DataIC50: 3.49E+3nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed