BDBM50188807 4-(3,4-dichloro-phenyl)-8-[2-(4-fluoro-phenyl)-cyclohexyl]-2,8-diaza-spiro[4.5]decan-1-one::CHEMBL213962

SMILES Fc1ccc(cc1)C1CCCCC1N1CCC2(CC1)C(CNC2=O)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=SXFSLOXYRHKGHZ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50188807   

TargetSodium- and chloride-dependent glycine transporter 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188807(4-(3,4-dichloro-phenyl)-8-[2-(4-fluoro-phenyl)-cyc...)
Affinity DataEC50:  2.19E+3nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed