BDBM50188463 4-[(3-chlorophenyl)amino]-6-(methylamino)quinazoline::CHEMBL209343

SMILES CNc1ccc2ncnc(Nc3cccc(Cl)c3)c2c1

InChI Key InChIKey=SFZSLQNVKFDVLY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50188463   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188463(4-[(3-chlorophenyl)amino]-6-(methylamino)quinazoli...)
Affinity DataIC50: 890nMAssay Description:Inhibition of serum-stimulated proliferation of mouse ERBB2 transfected NIH3T3 cell line after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188463(4-[(3-chlorophenyl)amino]-6-(methylamino)quinazoli...)
Affinity DataIC50: 4nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed