BDBM50188085 1-(4-Fluorobenzyl)-1H-imidazole::CHEMBL377770

SMILES Fc1ccc(Cn2ccnc2)cc1

InChI Key InChIKey=LOHJXVMUYVDWOW-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50188085   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50188085(1-(4-Fluorobenzyl)-1H-imidazole | CHEMBL377770)
Affinity DataIC50: 1.84E+4nMAssay Description:Inhibition of rat microsomal 17,20-lyase component of P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50188085(1-(4-Fluorobenzyl)-1H-imidazole | CHEMBL377770)
Affinity DataIC50: 8.66E+4nMAssay Description:Inhibition of rat microsomal 17-alpha-hydroxylase component of P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50188085(1-(4-Fluorobenzyl)-1H-imidazole | CHEMBL377770)
Affinity DataIC50: 9.65E+4nMAssay Description:Inhibition of rat testis 17-alpha-hydroxylase component of P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50188085(1-(4-Fluorobenzyl)-1H-imidazole | CHEMBL377770)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of rat testis 17,20 lyase component of P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
University of The West of Scotland

Curated by ChEMBL
LigandPNGBDBM50188085(1-(4-Fluorobenzyl)-1H-imidazole | CHEMBL377770)
Affinity DataIC50: 880nMAssay Description:Inhibition of aromataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Eindhoven University of Technology

Curated by ChEMBL
LigandPNGBDBM50188085(1-(4-Fluorobenzyl)-1H-imidazole | CHEMBL377770)
Affinity DataIC50: 494nMAssay Description:Inhibition of human CYP11B1 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Eindhoven University of Technology

Curated by ChEMBL
LigandPNGBDBM50188085(1-(4-Fluorobenzyl)-1H-imidazole | CHEMBL377770)
Affinity DataIC50: 330nMAssay Description:Inhibition of human CYP11B2 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed