BDBM50188026 2-ethoxy-3-(1-((2-(4-fluorophenyl)-5-methyloxazol-4-yl)methyl)-1H-indol-5-yl)propanoic acid::CHEMBL214272

SMILES CCOC(Cc1ccc2n(Cc3nc(oc3C)-c3ccc(F)cc3)ccc2c1)C(O)=O

InChI Key InChIKey=VKXXMTBEMZTIPR-UHFFFAOYSA-N

Data  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50188026   

TargetPeroxisome proliferator-activated receptor alpha(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188026(2-ethoxy-3-(1-((2-(4-fluorophenyl)-5-methyloxazol-...)
Affinity DataIC50: 121nMAssay Description:Binding affinity to PPARalpha by radio ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188026(2-ethoxy-3-(1-((2-(4-fluorophenyl)-5-methyloxazol-...)
Affinity DataIC50: 377nMAssay Description:Binding affinity to PPARgamma by radio ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188026(2-ethoxy-3-(1-((2-(4-fluorophenyl)-5-methyloxazol-...)
Affinity DataEC50:  630nMAssay Description:Activity at PPARalpha by luciferase reporter gene transactivation assay relative to farglitazarMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188026(2-ethoxy-3-(1-((2-(4-fluorophenyl)-5-methyloxazol-...)
Affinity DataEC50:  770nMAssay Description:Activity at PPARgamma by luciferase reporter gene transactivation assay relative to edaglitazoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188026(2-ethoxy-3-(1-((2-(4-fluorophenyl)-5-methyloxazol-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Activity at PPARdelta by luciferase reporter gene transactivation assay relative to GW 501516More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed