BDBM50187991 1-(4-(4-aminoisoxazolo[5,4-d]pyrimidin-3-yl)phenyl)-3-(3-ethylphenyl)urea::CHEMBL210003

SMILES CCc1cccc(NC(=O)Nc2ccc(cc2)-c2noc3ncnc(N)c23)c1

InChI Key InChIKey=XDGUQWMBCHDRBW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50187991   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187991(1-(4-(4-aminoisoxazolo[5,4-d]pyrimidin-3-yl)phenyl...)
Affinity DataIC50: 250nMAssay Description:Inhibition of KDR by cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187991(1-(4-(4-aminoisoxazolo[5,4-d]pyrimidin-3-yl)phenyl...)
Affinity DataIC50: 24nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed