BDBM50187856 CHEMBL378688::N-(cyclohexylmethyl)-3-hydroxy-5-(2-methoxy-4-nitrophenylamino)isothiazole-4-carboxamidine

SMILES COc1cc(ccc1Nc1s[nH]c(=O)c1C(=N)NCC1CCCCC1)[N+]([O-])=O

InChI Key InChIKey=HRWBEPZHUGPFIO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50187856   

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Valeant Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50187856(N-(cyclohexylmethyl)-3-hydroxy-5-(2-methoxy-4-nitr...)
Affinity DataIC50: 670nMAssay Description:Inhibition of MEK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed