BDBM50187845 5-(2-chloro-4-(trifluoromethyl)phenylamino)-3-hydroxy-N-(1-hydroxypropan-2-yl)isothiazole-4-carboxamidine::CHEMBL213168

SMILES CC(CO)NC(=N)c1c(Nc2ccc(cc2Cl)C(F)(F)F)s[nH]c1=O

InChI Key InChIKey=FTZJIQKFWAAGHZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50187845   

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Valeant Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50187845(5-(2-chloro-4-(trifluoromethyl)phenylamino)-3-hydr...)
Affinity DataIC50: 86nMAssay Description:Inhibition of MEK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed