BDBM50187821 3-hydroxy-5-(4-iodophenylamino)-N-isopropylisothiazole-4-carboxamidine::3-hydroxy-5-4-iodophenylamino)-N-isopropylisothiazole-4-carboximidamide::CHEMBL209868

SMILES CC(C)NC(=N)c1c(Nc2ccc(I)cc2)s[nH]c1=O

InChI Key InChIKey=BKIHVXHHEBYWDJ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50187821   

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50187821(3-hydroxy-5-4-iodophenylamino)-N-isopropylisothiaz...)
Affinity DataIC50: 510nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50187821(3-hydroxy-5-4-iodophenylamino)-N-isopropylisothiaz...)
Affinity DataIC50: 510nMAssay Description:Inhibition of MEK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50187821(3-hydroxy-5-4-iodophenylamino)-N-isopropylisothiaz...)
Affinity DataEC50:  8.32E+3nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed