BDBM50187787 1-(but-2-ynyl)-4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxypiperidine-4-carboxamide::CHEMBL209490

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC#CC)CC1)C(=O)NO

InChI Key InChIKey=YLPGDDBCDVVMDA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50187787   

LigandPNGBDBM50187787(1-(but-2-ynyl)-4-((4-(but-2-ynyloxy)phenylsulfonyl...)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187787(1-(but-2-ynyl)-4-((4-(but-2-ynyloxy)phenylsulfonyl...)
Affinity DataIC50: 249nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187787(1-(but-2-ynyl)-4-((4-(but-2-ynyloxy)phenylsulfonyl...)
Affinity DataIC50: 327nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed