BDBM50187699 CHEMBL3828340

SMILES C[C@@]1(O)C[C@](C1)([C@H](O)c1ccccn1)c1cc(ccn1)C(F)(F)F

InChI Key InChIKey=MTJXDHFAWXGXIN-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50187699   

TargetTransient receptor potential cation channel subfamily V member 3(Human)
Abbvie

Curated by ChEMBL

LigandBDBM50187699(CHEMBL3828340)Copy SMILESCopy InChI

Affinity DataIC50: 380nMAssay Description:Antagonist activity at human TRPV3 expressed in recombinant HEK293 cells assessed as inhibition of 2-APB induced currents by patch-clamp electrophysi...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
10/9/2017
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetTransient receptor potential cation channel subfamily V member 3(Human)
Abbvie

Curated by ChEMBL

LigandBDBM50187699(CHEMBL3828340)Copy SMILESCopy InChI

Affinity DataIC50: 930nMAssay Description:Antagonist activity at human TRPV3 expressed in recombinant HEK293 cells assessed as inhibition of 2-APB induced calcium flux by FLIPR analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
10/9/2017
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL