BDBM50187692 CHEMBL3827757

SMILES Cc1c(Sc2cccc(n2)C(O)=O)c2ccc(Cl)cc2n1-c1cnn(C)c1

InChI Key InChIKey=HEAMPEAZFMWFJG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50187692   

TargetAutotaxin(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50187692(CHEMBL3827757)
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant ATX in human MDA-MB-4355 cells using lysophosphatidylcholine as substrate preincubated for 15 mins followed by substrate ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2017
Entry Details Article
PubMed
TargetAutotaxin(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50187692(CHEMBL3827757)
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human ATX using bisP-nitrophenyl phosphate as substrate measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50187692(CHEMBL3827757)
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant human ATX using bisP-nitrophenyl phosphate as substrate measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50187692(CHEMBL3827757)
Affinity DataIC50: 300nMAssay Description:Inhibition of ATX in human MDA-MB-435S cells using lysophosphatidyl choline as substrate preincubated for 15 mins followed by substrate addition meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2019
Entry Details Article
PubMed