BDBM50187361 (4-Chloro-1H-indol-2-yl)-(5-hydroxy-1H-indol-2-yl)-methanone::CHEMBL377652

SMILES Oc1ccc2[nH]c(cc2c1)C(=O)c1cc2c(Cl)cccc2[nH]1

InChI Key InChIKey=UARDKBOLUCZGIZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50187361   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187361((4-Chloro-1H-indol-2-yl)-(5-hydroxy-1H-indol-2-yl)...)
Affinity DataIC50: 920nMAssay Description:Inhibition of endogenous FLT3 in EOL1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187361((4-Chloro-1H-indol-2-yl)-(5-hydroxy-1H-indol-2-yl)...)
Affinity DataIC50: 500nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed