BDBM50187189 2'-[(4-fluorophenyl)methyl]-4'-hydroxy-3'-oxo-2',3'-dihydrospiro[cyclopropane-1,1'-pyrrolo[3,4-g]quinoline]-9'-yl N,N-dimethylsulfamate::CHEMBL379974

SMILES CN(C)S(=O)(=O)Oc1c2c(C(=O)N(Cc3ccc(F)cc3)C22CC2)c(O)c2ncccc12

InChI Key InChIKey=UYXRWKBJDQYPRT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50187189   

TargetIntegrase(Human immunodeficiency virus type 1)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50187189(2'-[(4-fluorophenyl)methyl]-4'-hydroxy-3'-oxo-2',3...)
Affinity DataIC50: 357nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in MT4 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed