BDBM50187149 6-cyclohexyl-4-(2-(dimethylamino)-2-oxoethyl)-5-phenyl-4H-thieno[3,2-b]pyrrole-2-carboxylic acid::CHEMBL213832

SMILES CN(C)C(=O)Cn1c(c(C2CCCCC2)c2sc(cc12)C(O)=O)-c1ccccc1

InChI Key InChIKey=MLNJWPGFXYKPAF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50187149   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50187149(6-cyclohexyl-4-(2-(dimethylamino)-2-oxoethyl)-5-ph...)
Affinity DataIC50: 58nMAssay Description:Inhibition of HCV BK NS5B deltaC55 RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50187149(6-cyclohexyl-4-(2-(dimethylamino)-2-oxoethyl)-5-ph...)
Affinity DataIC50: 58nMAssay Description:Inhibition of HCV genotype 1b BK NS5B expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2016
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50187149(6-cyclohexyl-4-(2-(dimethylamino)-2-oxoethyl)-5-ph...)
Affinity DataIC50: 58nMAssay Description:Binding affinity to HCV NS5A polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed