BDBM50187130 CHEMBL3823578

SMILES COc1ccc2[nH]cc(CCNC(=O)C3CCN(Cc4ccccc4C)CC3)c2c1

InChI Key InChIKey=VITNUIFTUFCBDI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50187130   

TargetAcetylcholinesterase(Electric eel)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50187130(CHEMBL3823578)
Affinity DataIC50: 4.42E+3nMAssay Description:Inhibition of electric eel ACHE preincubated for 6 mins followed by addition of acetylcholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetCholinesterase(Horse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50187130(CHEMBL3823578)
Affinity DataIC50: 3.21E+3nMAssay Description:Inhibition of equine BCHE preincubated for 6 mins followed by addition of S-butyrylcholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50187130(CHEMBL3823578)
Affinity DataIC50: 7.42E+3nMAssay Description:Inhibition of human erythrocyte ACHE preincubated for 6 mins followed by addition of acetylcholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetCholinesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50187130(CHEMBL3823578)
Affinity DataIC50: 3.01E+3nMAssay Description:Inhibition of human serum BCHE preincubated for 6 mins followed by addition of S-butyrylcholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed