BDBM50187069 1-(3,4-dichlorophenyl)-4-(4-hydroxy-3-methoxybenzylidene)pyrazolidine-3,5-dione::4-(4-hydroxy-3-methoxybenzylidene)-1-(3,4-dichlorophenyl)pyrazolidine-3,5-dione::CHEMBL380093

SMILES COc1cc(C=C2C(=O)NN(C2=O)c2ccc(Cl)c(Cl)c2)ccc1O

InChI Key InChIKey=HXGLQQGNMQRHCK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50187069   

LigandPNGBDBM50187069(1-(3,4-dichlorophenyl)-4-(4-hydroxy-3-methoxybenzy...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Dyrk1 autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Mouse)
Research Center Idrtech

Curated by ChEMBL
LigandPNGBDBM50187069(1-(3,4-dichlorophenyl)-4-(4-hydroxy-3-methoxybenzy...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of mouse Dyrk1A autophosphorylation in HEk293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50187069(1-(3,4-dichlorophenyl)-4-(4-hydroxy-3-methoxybenzy...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of DYRK1A (unknown origin) autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed