BDBM50187037 (S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-(dimethylamino)ethylamino)-2-(4-fluorophenyl)acetamide::CHEMBL378784

SMILES CN(C)CCN[C@H](C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F)c1ccc(F)cc1

InChI Key InChIKey=SWGQDPWKPYZEEH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50187037   

TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50187037((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-(dimet...)
Affinity DataIC50: 770nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50187037((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-(dimet...)
Affinity DataIC50: 650nMAssay Description:Binding affinity to human NK1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50187037((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-(dimet...)
Affinity DataIC50: 720nMAssay Description:Inhibition of [125I]MCP1 binding to CCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50187037((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-(dimet...)
Affinity DataIC50: 720nMAssay Description:Displacement of [125I]MCP-1 from human CCR2b expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50187037((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-(dimet...)
Affinity DataIC50: 770nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed