BDBM50187033 (S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-(piperidin-1-yl)ethylamino)-2-(thiophen-3-yl)acetamide::CHEMBL211775

SMILES FC(F)(F)c1cc(CNC(=O)[C@@H](NCCN2CCCCC2)c2ccsc2)cc(c1)C(F)(F)F

InChI Key InChIKey=NLWNSKCTNYPJQF-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50187033   

TargetSubstance-P receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50187033((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-(piper...)
Affinity DataIC50: 100nMAssay Description:Binding affinity to human NK1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50187033((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-(piper...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to human NK3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50187033((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-(piper...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to CCR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50187033((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-(piper...)
Affinity DataIC50: 2.00E+3nMAssay Description:Binding affinity to CCR4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50187033((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-(piper...)
Affinity DataIC50: 50nMAssay Description:Antagonist activity against CCR2 assessed as inhibition of MCP1-induced calcium flux in human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50187033((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-(piper...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to human NK2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50187033((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-(piper...)
Affinity DataIC50: 39nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50187033((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-(piper...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to CCR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50187033((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-(piper...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to CCR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 8(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50187033((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-(piper...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to CCR8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50187033((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-(piper...)
Affinity DataIC50: 30nMAssay Description:Binding affinity to CCR2 in human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50187033((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-(piper...)
Affinity DataIC50: 39nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed