BDBM50187003 3-(3,4-dioxo-2-(pentan-3-ylamino)cyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide::CHEMBL214047::CHEMBL218964

SMILES CCC(CC)Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O

InChI Key InChIKey=RZXVFVRPSNXVEC-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50187003   

TargetC-X-C chemokine receptor type 2(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50187003(CHEMBL214047 | CHEMBL218964 | 3-(3,4-dioxo-2-(pent...)
Affinity DataIC50: 5nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50187003(CHEMBL214047 | CHEMBL218964 | 3-(3,4-dioxo-2-(pent...)
Affinity DataIC50: 15nMAssay Description:Displacement of [125I]hCXCL8 from human CXCR2 receptor expressed in BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50187003(CHEMBL214047 | CHEMBL218964 | 3-(3,4-dioxo-2-(pent...)
Affinity DataIC50: 910nMAssay Description:Displacement of [125I]hCXCL8 from human CXCR1 receptor expressed in BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50187003(CHEMBL214047 | CHEMBL218964 | 3-(3,4-dioxo-2-(pent...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human CXCR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50187003(CHEMBL214047 | CHEMBL218964 | 3-(3,4-dioxo-2-(pent...)
Affinity DataIC50: 19nMAssay Description:Inhibition of human CXCR2-mediated chemotaxis expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed