BDBM50186924 3-(4-(5-(5-isobutylpyridin-2-yl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid::CHEMBL209566

SMILES CC(C)Cc1ccc(nc1)-c1nc(no1)-c1ccc(CCC(O)=O)cc1C

InChI Key InChIKey=DNEWRWUHAVFNJE-UHFFFAOYSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50186924   

TargetSphingosine 1-phosphate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50186924(3-(4-(5-(5-isobutylpyridin-2-yl)-1,2,4-oxadiazol-3...)
Affinity DataEC50: >1.00E+4nMAssay Description:Activity at S1P2 receptor expressed in CHO cells measured as S1P-induced [35S]GTP-gamma-S uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50186924(3-(4-(5-(5-isobutylpyridin-2-yl)-1,2,4-oxadiazol-3...)
Affinity DataEC50:  3.40nMAssay Description:Agonist activity at S1P1 receptor expressed in CHO cells measured as S1P-induced [35S]GTP-gamma-S uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50186924(3-(4-(5-(5-isobutylpyridin-2-yl)-1,2,4-oxadiazol-3...)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at S1P3 receptor expressed in CHO cells measured as S1P-induced [35S]GTP-gamma-S uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50186924(3-(4-(5-(5-isobutylpyridin-2-yl)-1,2,4-oxadiazol-3...)
Affinity DataEC50: >1.00E+4nMAssay Description:Activity at S1P4 receptor expressed in CHO cells measured as S1P-induced [35S]GTP-gamma-S uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50186924(3-(4-(5-(5-isobutylpyridin-2-yl)-1,2,4-oxadiazol-3...)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at S1P5 receptor expressed in CHO cells measured as S1P-induced [35S]GTP-gamma-S uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed