BDBM50186915 3-(4-(5-(6-isobutylpyridin-3-yl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid::CHEMBL211255

SMILES CC(C)Cc1ccc(cn1)-c1nc(no1)-c1ccc(CCC(O)=O)cc1C

InChI Key InChIKey=SWTQAFJPNKNETR-UHFFFAOYSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50186915   

TargetSphingosine 1-phosphate receptor 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50186915(3-(4-(5-(6-isobutylpyridin-3-yl)-1,2,4-oxadiazol-3...)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at S1P3 receptor expressed in CHO cells measured as S1P-induced [35S]GTP-gamma-S uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50186915(3-(4-(5-(6-isobutylpyridin-3-yl)-1,2,4-oxadiazol-3...)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at S1P5 receptor expressed in CHO cells measured as S1P-induced [35S]GTP-gamma-S uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50186915(3-(4-(5-(6-isobutylpyridin-3-yl)-1,2,4-oxadiazol-3...)
Affinity DataEC50:  88nMAssay Description:Agonist activity at S1P1 receptor expressed in CHO cells measured as S1P-induced [35S]GTP-gamma-S uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50186915(3-(4-(5-(6-isobutylpyridin-3-yl)-1,2,4-oxadiazol-3...)
Affinity DataEC50: >1.00E+4nMAssay Description:Activity at S1P2 receptor expressed in CHO cells measured as S1P-induced [35S]GTP-gamma-S uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50186915(3-(4-(5-(6-isobutylpyridin-3-yl)-1,2,4-oxadiazol-3...)
Affinity DataEC50: >1.00E+4nMAssay Description:Activity at S1P4 receptor expressed in CHO cells measured as S1P-induced [35S]GTP-gamma-S uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed