BDBM50186659 3-dimethylamino-5-(4-fluoro-phenyl)-thiophene-2-carboxylic acid amide::CHEMBL381932

SMILES CN(C)c1cc(sc1C(N)=O)-c1ccc(F)cc1

InChI Key InChIKey=GPPHGSWSUHHEAN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50186659   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186659(3-dimethylamino-5-(4-fluoro-phenyl)-thiophene-2-ca...)
Affinity DataIC50: 2.35E+4nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186659(3-dimethylamino-5-(4-fluoro-phenyl)-thiophene-2-ca...)
Affinity DataIC50: 2.35E+4nMAssay Description:Inhibition of human IKK-beta using TMB as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed