BDBM50186581 CHEMBL377413::cis-methyl 4-(3-(4-chlorophenylsulfonyl)-3-(2,5-difluorophenyl)-1-methylcyclohexyl)butanoate

SMILES COC(=O)CCC[C@]1(C)CCC[C@](C1)(c1cc(F)ccc1F)S(=O)(=O)c1ccc(Cl)cc1

InChI Key InChIKey=RPMAGSXCVXNPGV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50186581   

LigandPNGBDBM50186581(cis-methyl 4-(3-(4-chlorophenylsulfonyl)-3-(2,5-di...)
Affinity DataIC50: 10nMAssay Description:Inhibition of gamma secretase expressed in SH-SY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed