BDBM50186579 CHEMBL377892::trans-1-(3-allyl-1-(2,5-difluorophenyl)cyclohexylsulfonyl)-4-chlorobenzene
SMILES Fc1ccc(F)c(c1)[C@@]1(CCC[C@H](CC=C)C1)S(=O)(=O)c1ccc(Cl)cc1
InChI Key InChIKey=QYZZHKZREHQWLD-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50186579
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 85nMAssay Description:Inhibition of gamma secretase expressed in SH-SY5Y cellsMore data for this Ligand-Target Pair
