BDBM50186412 3-(4-(5-(5-chloro-6-isopropoxypyridin-3-yl)-1,3,4-thiadiazol-2-yl)-3-methylphenyl)propanoic acid::CHEMBL212420

SMILES CC(C)Oc1ncc(cc1Cl)-c1nnc(s1)-c1ccc(CCC(O)=O)cc1C

InChI Key InChIKey=HQLLYIQEWOHZTJ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50186412   

TargetSphingosine 1-phosphate receptor 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50186412(3-(4-(5-(5-chloro-6-isopropoxypyridin-3-yl)-1,3,4-...)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at S1P5 receptor assessed as induction of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50186412(3-(4-(5-(5-chloro-6-isopropoxypyridin-3-yl)-1,3,4-...)
Affinity DataEC50:  2.10nMAssay Description:Agonist activity at S1P1 receptor assessed as induction of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed