BDBM50186371 CHEMBL264120::c(his-D-phe-arg-trp-Aoc)

SMILES NC(N)=NCCC[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC[C@H](Cc2cnc[nH]2)NC(=O)CCCCCCCC(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O

InChI Key InChIKey=VFJZBZLGBBBPQI-UHFFFAOYSA-N

Data  1 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50186371   

TargetMelanocortin receptor 4(Human)
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50186371(c(his-D-phe-arg-trp-Aoc) | CHEMBL264120)
Affinity DataEC50:  16.4nMAssay Description:Activity at human MC4R by cAMP accumulation in SaoS2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50186371(c(his-D-phe-arg-trp-Aoc) | CHEMBL264120)
Affinity DataEC50:  77.4nMAssay Description:Activity at human MC1R by cAMP accumulation in SaoS2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50186371(c(his-D-phe-arg-trp-Aoc) | CHEMBL264120)
Affinity DataKi:  319nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human cloned MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed