BDBM50186110 CHEMBL382612::rac-N-((3-(N-(3-chlorobenzyl)-2,2,2-trichloroacetamido)cyclohexyl)methyl)-4-fluoro-N-(3-(2-(pyrrolidin-1-yl)ethoxy)phenyl)benzamide

SMILES Fc1ccc(cc1)C(=O)N(CC1CCCC(C1)N(Cc1cccc(Cl)c1)C(=O)C(Cl)(Cl)Cl)c1cccc(OCCN2CCCC2)c1

InChI Key InChIKey=IMQBTGWOTKESLU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50186110   

TargetMotilin receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186110(rac-N-((3-(N-(3-chlorobenzyl)-2,2,2-trichloroaceta...)
Affinity DataIC50: 58nMAssay Description:Inhibition of [125]I-motilin binding to rabbit motilin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186110(rac-N-((3-(N-(3-chlorobenzyl)-2,2,2-trichloroaceta...)
Affinity DataIC50: 36nMAssay Description:Activity at rabbit duodenum motilin receptor by tissue contractility assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186110(rac-N-((3-(N-(3-chlorobenzyl)-2,2,2-trichloroaceta...)
Affinity DataIC50: 267nMAssay Description:Activity at human motilin receptor transfected in HEK293 cells assessed as inhibition of motilin-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed