BDBM50186102 CHEMBL378317::N-((3-(N-(3-nitrobenzyl)-2,2,2-trichloroacetamido)cyclohexyl)methyl)-4-fluoro-N-(3-(2-(pyrrolidin-1-yl)ethoxy)phenyl)benzamide

SMILES [O-][N+](=O)c1cccc(CN(C2CCCC(CN(C(=O)c3ccc(F)cc3)c3cccc(OCCN4CCCC4)c3)C2)C(=O)C(Cl)(Cl)Cl)c1

InChI Key InChIKey=BDLIUAXYTCOMLC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50186102   

TargetMotilin receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186102(N-((3-(N-(3-nitrobenzyl)-2,2,2-trichloroacetamido)...)
Affinity DataIC50: 14nMAssay Description:Inhibition of [125]I-motilin binding to rabbit motilin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186102(N-((3-(N-(3-nitrobenzyl)-2,2,2-trichloroacetamido)...)
Affinity DataIC50: 72nMAssay Description:Activity at rabbit duodenum motilin receptor by tissue contractility assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186102(N-((3-(N-(3-nitrobenzyl)-2,2,2-trichloroacetamido)...)
Affinity DataIC50: 52nMAssay Description:Activity at human motilin receptor transfected in HEK293 cells assessed as inhibition of motilin-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed