BDBM50185976 CHEMBL205706::N-(3,4-dichlorophenyl)-N-(3-{4-[4-(dimethylcarbamoyl)benzyl]piperidin-1-yl}propyl)-1-(methylsulfonyl)piperidine-4-carboxamide

SMILES CN(C)C(=O)c1ccc(CC2CCN(CCCN(C(=O)C3CCN(CC3)S(C)(=O)=O)c3ccc(Cl)c(Cl)c3)CC2)cc1

InChI Key InChIKey=SEVIDRCPHNOAJR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50185976   

TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185976(N-(3,4-dichlorophenyl)-N-(3-{4-[4-(dimethylcarbamo...)
Affinity DataIC50: 19nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185976(N-(3,4-dichlorophenyl)-N-(3-{4-[4-(dimethylcarbamo...)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed