BDBM50185972 CHEMBL207182::N-(3-(4-(4-fluorobenzyl)piperidin-1-yl)propyl)-1-acetyl-N-(3,4-dichlorophenyl)piperidine-4-carboxamide

SMILES CC(=O)N1CCC(CC1)C(=O)N(CCCN1CCC(Cc2ccc(F)cc2)CC1)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=JGUOUIAGQGEANO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50185972   

TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185972(N-(3-(4-(4-fluorobenzyl)piperidin-1-yl)propyl)-1-a...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185972(N-(3-(4-(4-fluorobenzyl)piperidin-1-yl)propyl)-1-a...)
Affinity DataIC50: 3nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed