BDBM50185898 2-[4-(4-butyl-phenylethynyl)-phenylsulfanyl]-4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-butyric acid::CHEMBL208615

SMILES CCCCc1ccc(cc1)C#Cc1ccc(SC(CCN2C(=O)c3ccccc3C2=O)C(O)=O)cc1

InChI Key InChIKey=NJXYRSYNXFYWJX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50185898   

TargetMatrix metalloproteinase-9(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185898(2-[4-(4-butyl-phenylethynyl)-phenylsulfanyl]-4-(1,...)
Affinity DataIC50: 22nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185898(2-[4-(4-butyl-phenylethynyl)-phenylsulfanyl]-4-(1,...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed