BDBM50185879 2-{4-[4-(4-chloro-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-benzenesulfonyl}-4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-butyric acid::CHEMBL208136

SMILES OC(=O)C(CCN1C(=O)c2ccccc2C1=O)S(=O)(=O)c1ccc(cc1)N1CCC(=CC1)c1ccc(Cl)cc1

InChI Key InChIKey=ORZIBOAGVYKRKN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50185879   

TargetMatrix metalloproteinase-9(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185879(2-{4-[4-(4-chloro-phenyl)-3,6-dihydro-2H-pyridin-1...)
Affinity DataIC50: 258nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185879(2-{4-[4-(4-chloro-phenyl)-3,6-dihydro-2H-pyridin-1...)
Affinity DataIC50: 12nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed