BDBM50185796 5-chloro-3-(1-(1,2-dihydroacenaphthylen-1-yl)piperidin-4-yl)-2-methyl-1H-indole::CHEMBL212575

SMILES Cc1[nH]c2ccc(Cl)cc2c1C1CCN(CC1)C1Cc2cccc3cccc1c23

InChI Key InChIKey=OGLIFFKVFKYPEO-UHFFFAOYSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50185796   

TargetNociceptin receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185796(5-chloro-3-(1-(1,2-dihydroacenaphthylen-1-yl)piper...)
Affinity DataEC50:  5.46E+4nMAssay Description:Agonist activity at ORL1 receptor expressed in HEK293 cells by calciun flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185796(5-chloro-3-(1-(1,2-dihydroacenaphthylen-1-yl)piper...)
Affinity DataKi:  10nMAssay Description:Agonist activity at ORL1 receptor expressed in HEK293 cells by calciun flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185796(5-chloro-3-(1-(1,2-dihydroacenaphthylen-1-yl)piper...)
Affinity DataKi:  260nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185796(5-chloro-3-(1-(1,2-dihydroacenaphthylen-1-yl)piper...)
Affinity DataKi:  680nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185796(5-chloro-3-(1-(1,2-dihydroacenaphthylen-1-yl)piper...)
Affinity DataKi:  2.75E+3nMAssay Description:Displacement of [3H]DDPDE from delta opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed