BDBM50185779 4-(2,4-difluorophenethyl)-1-(4-fluorophenylsulfonyl)-1,2,3,6-tetrahydropyridine::CHEMBL210849

SMILES Fc1ccc(cc1)S(=O)(=O)N1CCC(CCc2ccc(F)cc2F)=CC1

InChI Key InChIKey=SMWLFHWQLUJVNG-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50185779   

Target5-hydroxytryptamine receptor 2A(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185779(4-(2,4-difluorophenethyl)-1-(4-fluorophenylsulfony...)
Affinity DataKi:  22nMAssay Description:Binding affinity to human 5HT2AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185779(4-(2,4-difluorophenethyl)-1-(4-fluorophenylsulfony...)
Affinity DataKi:  449nMAssay Description:Binding affinity to human 5HT2CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185779(4-(2,4-difluorophenethyl)-1-(4-fluorophenylsulfony...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to human D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185779(4-(2,4-difluorophenethyl)-1-(4-fluorophenylsulfony...)
Affinity DataKi: >9.00E+3nMAssay Description:Binding affinity to human IKrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed