BDBM50185526 2-(trans-5-(4-(5-(4-cyclohexylphenyl)-1,2,4-oxadiazol-3-yl)phenyl)pyrrolidin-3-yl)acetic acid::CHEMBL377828

SMILES OC(=O)C[C@@H]1CN[C@H](C1)c1ccc(cc1)-c1noc(n1)-c1ccc(cc1)C1CCCCC1

InChI Key InChIKey=AEINVRKYWDZAKS-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50185526   

TargetSphingosine 1-phosphate receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185526(2-(trans-5-(4-(5-(4-cyclohexylphenyl)-1,2,4-oxadia...)
Affinity DataIC50: 1.40nMAssay Description:Displacement of [33P]S1P from human S1P1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185526(2-(trans-5-(4-(5-(4-cyclohexylphenyl)-1,2,4-oxadia...)
Affinity DataIC50: 57nMAssay Description:Displacement of [33P]S1P from human S1P5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185526(2-(trans-5-(4-(5-(4-cyclohexylphenyl)-1,2,4-oxadia...)
Affinity DataIC50: 110nMAssay Description:Displacement of [33P]S1P from human S1P4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185526(2-(trans-5-(4-(5-(4-cyclohexylphenyl)-1,2,4-oxadia...)
Affinity DataIC50: 3.10E+3nMAssay Description:Displacement of [33P]S1P from human S1P3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185526(2-(trans-5-(4-(5-(4-cyclohexylphenyl)-1,2,4-oxadia...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [33P]S1P from human S1P2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed