BDBM50185366 CHEMBL2371911::CHEMBL436499::Sub[-Trp-Arg-Nva-Arg-Tyr-NH2]2

SMILES CCC[C@H](NC(=O)[C@H](CCCN=C(/N)N)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)C(N)CCCCC(N)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N[C@@H](CCCN=C(/N)N)C(=O)N[C@@H](CCC)C(=O)N[C@@H](CCCN=C(/N)N)C(=O)N[C@@H](Cc5ccc(O)cc5)C(N)=O)C(=O)N[C@@H](CCCN=C(/N)N)C(=O)N[C@@H](Cc6ccc(O)cc6)C(N)=O

InChI Key InChIKey=OWXAFDOATMPIJT-UHFFFAOYSA-N

Data  6 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50185366   

TargetNeuropeptide Y receptor type 4(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50185366(Sub[-Trp-Arg-Nva-Arg-Tyr-NH2]2 | CHEMBL436499 | CH...)
Affinity DataEC50:  370nMAssay Description:Agonist activity at human NPY4 receptor in HEK293 cells by inhibition of forskolin-stimulated cAMP synthesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 4(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50185366(Sub[-Trp-Arg-Nva-Arg-Tyr-NH2]2 | CHEMBL436499 | CH...)
Affinity DataEC50:  430nMAssay Description:Agonist activity at human NPY4 receptor in HEK293 cells by inhibition of forskolin-stimulated cAMP synthesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50185366(Sub[-Trp-Arg-Nva-Arg-Tyr-NH2]2 | CHEMBL436499 | CH...)
Affinity DataEC50:  1.41E+3nMAssay Description:Agonist activity at human NPY1 receptor in CHO cells by inhibition of forskolin-stimulated cAMP synthesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 4(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50185366(Sub[-Trp-Arg-Nva-Arg-Tyr-NH2]2 | CHEMBL436499 | CH...)
Affinity DataKi:  2nMAssay Description:Displacement of [125I]hPP from human NPY4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 4(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50185366(Sub[-Trp-Arg-Nva-Arg-Tyr-NH2]2 | CHEMBL436499 | CH...)
Affinity DataKi:  2nMAssay Description:Displacement of [125I]hPP from human NPY4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50185366(Sub[-Trp-Arg-Nva-Arg-Tyr-NH2]2 | CHEMBL436499 | CH...)
Affinity DataKi:  80nMAssay Description:Displacement of [125I]NPY from human NPY1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50185366(Sub[-Trp-Arg-Nva-Arg-Tyr-NH2]2 | CHEMBL436499 | CH...)
Affinity DataKi:  80nMAssay Description:Displacement of [125I]NPY from human NPY1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50185366(Sub[-Trp-Arg-Nva-Arg-Tyr-NH2]2 | CHEMBL436499 | CH...)
Affinity DataKi:  390nMAssay Description:Agonist activity at human NPY2 receptor in CHO cells by inhibition of forskolin-stimulated cAMP synthesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50185366(Sub[-Trp-Arg-Nva-Arg-Tyr-NH2]2 | CHEMBL436499 | CH...)
Affinity DataKi:  530nMAssay Description:Displacement of [125I]NPY from human NPY2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed