BDBM50185183 CHEMBL380372::methyl 3-(5-(4-(piperidin-1-yl)piperidin-1-yl)-1H-benzo[d]imidazol-2-yl)-1H-indazole-5-carboxylate

SMILES COC(=O)c1ccc2[nH]nc(-c3nc4ccc(cc4[nH]3)N3CCC(CC3)N3CCCCC3)c2c1

InChI Key InChIKey=HUQYQFBIFGUUQQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50185183   

LigandPNGBDBM50185183(methyl 3-(5-(4-(piperidin-1-yl)piperidin-1-yl)-1H-...)
Affinity DataIC50: 63nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50185183(methyl 3-(5-(4-(piperidin-1-yl)piperidin-1-yl)-1H-...)
Affinity DataIC50: 15nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Chiron

Curated by ChEMBL
LigandPNGBDBM50185183(methyl 3-(5-(4-(piperidin-1-yl)piperidin-1-yl)-1H-...)
Affinity DataIC50: 73nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50185183(methyl 3-(5-(4-(piperidin-1-yl)piperidin-1-yl)-1H-...)
Affinity DataIC50: 31nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed