BDBM50185142 (+/-)-3-(trans-5-(4-(5-(4-isobutylphenyl)-1,2,4-oxadiazol-3-yl)phenyl)pyrrolidin-2-yl)propanoic acid::CHEMBL210468

SMILES CC(C)Cc1ccc(cc1)-c1nc(no1)-c1ccc(cc1)[C@@H]1CC[C@@H](CCC(O)=O)N1

InChI Key InChIKey=QEBXXPLHWMZIKW-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50185142   

TargetSphingosine 1-phosphate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185142((+/-)-3-(trans-5-(4-(5-(4-isobutylphenyl)-1,2,4-ox...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [33P]S1P from S1P2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185142((+/-)-3-(trans-5-(4-(5-(4-isobutylphenyl)-1,2,4-ox...)
Affinity DataIC50: 80nMAssay Description:Displacement of [33P]S1P from S1P5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185142((+/-)-3-(trans-5-(4-(5-(4-isobutylphenyl)-1,2,4-ox...)
Affinity DataIC50: 630nMAssay Description:Displacement of [33P]S1P from S1P4 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185142((+/-)-3-(trans-5-(4-(5-(4-isobutylphenyl)-1,2,4-ox...)
Affinity DataIC50: 5.70nMAssay Description:Displacement of [33P]S1P from S1P1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185142((+/-)-3-(trans-5-(4-(5-(4-isobutylphenyl)-1,2,4-ox...)
Affinity DataIC50: 6.70E+3nMAssay Description:Displacement of [33P]S1P from S1P3 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed