BDBM50185133 CHEMBL379097::N-(2-fluorophenyl)-2-(1-(3-(2-(pyridin-2-yl)ethynyl)benzoyl)piperidin-4-yl)acetamide

SMILES Fc1ccccc1NC(=O)CC1CCN(CC1)C(=O)c1cccc(c1)C#Cc1ccccn1

InChI Key InChIKey=YQHKVGJQICUJMY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50185133   

TargetSubstance-K receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185133(N-(2-fluorophenyl)-2-(1-(3-(2-(pyridin-2-yl)ethyny...)
Affinity DataIC50: 550nMAssay Description:Inhibition of human NK2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185133(N-(2-fluorophenyl)-2-(1-(3-(2-(pyridin-2-yl)ethyny...)
Affinity DataIC50: 640nMAssay Description:Inhibition of human NK1 receptor expressed in U373MG cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed