BDBM50185114 2-(2-chlorobenzamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide::CHEMBL210832

SMILES NC(=O)c1c(NC(=O)c2ccccc2Cl)sc2CCCCc12

InChI Key InChIKey=VPJJUDAXEIWYQR-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50185114   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50185114(2-(2-chlorobenzamido)-4,5,6,7-tetrahydrobenzo[b]th...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FLT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50185114(2-(2-chlorobenzamido)-4,5,6,7-tetrahydrobenzo[b]th...)
Affinity DataEC50:  326nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells co-expressing YFP incubated for 10 mins by halide potentiator ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
LigandPNGBDBM50185114(2-(2-chlorobenzamido)-4,5,6,7-tetrahydrobenzo[b]th...)
Affinity DataEC50:  326nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed