BDBM50185048 CHEMBL3822838

SMILES COc1ccc(cc1OC)-c1coc2c(c(O)cc3occ(-c4ccc(OC)c(OC)c4)c(=O)c23)c1=O

InChI Key InChIKey=HPVJWIGUQJWCAE-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50185048   

TargetATP-dependent translocase ABCB1(Human)
China Medical University

Curated by ChEMBL
LigandPNGBDBM50185048(CHEMBL3822838)
Affinity DataIC50: 594nMAssay Description:Inhibition of full length human ABCB1 expressed in Flp-In-293 cells assessed as potentiation of doxorubicin-induced cytotoxicity by measuring doxorub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2017
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Medical University

Curated by ChEMBL
LigandPNGBDBM50185048(CHEMBL3822838)
Affinity DataIC50: 597nMAssay Description:Inhibition of full length human ABCB1 expressed in Flp-In-293 cells assessed as potentiation of doxorubicin-induced cytotoxicity by measuring doxorub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2017
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Medical University

Curated by ChEMBL
LigandPNGBDBM50185048(CHEMBL3822838)
Affinity DataIC50: 85nMAssay Description:Inhibition of full length human ABCB1 expressed in Flp-In-293 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2017
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Medical University

Curated by ChEMBL
LigandPNGBDBM50185048(CHEMBL3822838)
Affinity DataIC50: 203nMAssay Description:Inhibition of full length human ABCB1 expressed in Flp-In-293 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2017
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Medical University

Curated by ChEMBL
LigandPNGBDBM50185048(CHEMBL3822838)
Affinity DataIC50: 68nMAssay Description:Inhibition of full length human ABCB1 expressed in Flp-In-293 cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitax...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2017
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Medical University

Curated by ChEMBL
LigandPNGBDBM50185048(CHEMBL3822838)
Affinity DataIC50: 73nMAssay Description:Inhibition of full length human ABCB1 expressed in Flp-In-293 cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitax...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2017
Entry Details Article
PubMed